Today's post comes from Dr. Stuart Chipkin, Valley Medical Group's Endocrinologist and Diabetes Program Director.

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Article Title : Thoughts from a Doc: Why do my sugars DO that?!? (Part 2)
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Today's post comes from Dr. Stuart Chipkin, Valley Medical Group's Endocrinologist and Diabetes Program Director. 

This is Part 2 of 3 of this series from Dr. Chipkin. Last week we heard his thoughts on how exercise and food impact blood sugars - this week we get his perspective on some medications that can influence your numbers. 

Thoughts from a Doc: 
Why do my sugars DO that?!? (Part 2)

Insulin: (as my daughter would say- d�uh!).  Oral pills like glipizide [Glucatrol], glimepiride [Amaryl] or glyburide [Micronase] cause your pancreas to release insulin which can certainly lower glucose values over the course of many hours.  Other medications (repaglinide [Prandin] or nateglinide [Starlix]) act more rapidly and only cause insulin to be released for a few hours.  But the effectiveness of these pills is based on two things: (1) the ability of your pancreas to make and release insulin; and (2) the ability of your body to use the amount of insulin made by the pancreas.  If your pancreas �worn out�, then these medications won�t be very effective (the analogy is that you can�t squeeze anything out of a dry sponge).  Even if these pills help the pancreas to release insulin, if your body is very resistant to insulin, then it won�t be enough.  Resistance to insulin can occur for many reasons including excess weight, infections, and steroid medications such as prednisone, hydrocortisone or dexamethasone. 

Counter-insulin hormones: These can be thought of as �anti-insulin� hormones - fighting against the action of insulin.  The most common of these are steroid medications like prednisone, hydrocortisone or dexamethasone.  These medicines are sometimes used as pills for weeks at a time and can raise blood sugars a lot.  Sometimes, they are injected into joints or other locations and can raise glucose values for a few days.  Other counter-insulin hormones are stress hormones that are released when people are sick with other illnesses.

Next week's post will discuss a few other factors, including the "element of mystery" that anyone with diabetes knows all too well. Not as simple as it seems, sometimes!!

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"Thoughts from a Doc: Why do my sugars DO that?!? (Part 2)"

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